Title : Isolated acute cholecystitis, with a rare diagnosis
Abstract:
Acute cholecystitis, though a common surgical presentation, may have a rare etiology such as IgG4-Related-Disease [1].
Usually IgG4-Related-cholecystitis is associated with involvement of pancreas or biliary tree. Recently, we came across two cases of isolated IgG4-Related-Acute cholecystitis without pancreatic or biliary tree involvement, which were managed successfully.
Review of literature showed that only 17 cases of IgG4-Related cholecystitis are reported till date, out of which only 5 are of isolated gallbladder involvement.
These two cases operated by us are rare and underline the immense developments in histopathological sciences.
References
1. Umehara H, Okazaki K, Kawa S, et al. Research program for intractable disease by the ministry of health, labor and welfare (MHLW) Japan. The 2020 revised comprehensive diagnostic (RCD) criteria for IgG4-RD. Mod Rheumatol. 2021 May 4;31(3):529e533.
Audience Take Away:
Knowledge of IgG4-Related cholecystitis is important to correctly diagnose and manage this entity. Recent developments in pathological sciences such as immunohistochemistry are of pivotal role towards the diagnosis.
