This is to inform that due to some circumstances beyond the organizer control, “2nd Edition of International Conference on Gastroenterology” (Gastro 2024) during October 21-23, 2024 at Baltimore, MD, USA has been postponed. The updated dates and venue will be displayed shortly.
Your registration can be transferred to the next edition, if you have already confirmed your participation at the event.
For further details, please contact us at gastroenterology@magnusconference.com or call + 1 (702) 988-2320.
Prokinetic agents have been extensively studied for improving the quality of bowel preparations. However, few studies had investigated the effect of prokinetic agents on post-colonoscopy abdominal discomfort. The purpose of this study is to examine the effectiveness of Itopr [....] » Read More
Cholelithiasis presents in approximately 20 % of the total population, ranging between 10% and 30 %. It presents one of the most common causes for non malignant surgical treatment. The cornerstone therapy is laparoscopic cholecystectomy, urgent of elective. Laparoscopic cholecyst [....] » Read More
Identification of Lgr5 as the intestinal stem cell marker as well as the growth factors necessary to replicate adult intestinal stem cell division has led to the establishment of the methods to generate "indefinite" ex vivo primary intestinal epithelial cultures, termed [....] » Read More
A small study was performed to assess the satiation and overall wellbeing of participants receiving home parenteral or enteral nutrition (HPN) using the Bette. One hundred twelve participants were measured on a survey response using before and after use of the Bette. 54.95% of th [....] » Read More
Colorectal cancer is one of the most common and lethal cancer worldwide, and it exhibits differences in incidence, pathogenesis, molecular pathways, and outcome depending on the location of the tumour. Colorectal cancer is a disease strongly influenced by gender, mortality rates [....] » Read More
Ghrelin is a hormone produced in the gastrointestinal tract mainly by gastric gland cells with central and peripheral effects. The endocrine cells that produce it are mainly located in the gastric fundus. Their distribution in obese subjects is controversial. In this study we exa [....] » Read More
Aim: to evaluate the results of thrombectomy from mesenteric vessels in the treatment of acute mesenteric ischemia (arterial and venous causes). Material and Methods The results of treatment of 33 patients with acute mesenteric ischemia were analyzed. This patients underwent s [....] » Read More
Acute peritonitis is a relatively common intra-abdominal infection that a general surgeon will have to manage many times in his surgical carrier. Usually it is a secondary peritonitis caused either by direct peritoneal invasion from an inflamed infected viscera or by gastrointest [....] » Read More
Introduction Inflammatory Bowel Disease (IBD) is a chronic gastrointestinal illness comprising two distinct clinical entities, Crohn’s disease, and Ulcerative colitis. Various treatment modalities like corticosteroids and immunomodulator drugs like azathioprine, methotrexa [....] » Read More
Introduction Inflammatory Bowel Disease (IBD), consisting of Crohn’s disease and Ulcerative colitis, causes recurrent episodes of gastrointestinal tract inflammation to varying degrees. It is associated with multiple episodes throughout life and hence, patients require mai [....] » Read More
Background: Hepcidin and ferroportin are master regulators of systemic iron homeostasis in mammals. Hepcidin is encoded for by the HAMP gene and is released by hepatocytes to regulate systemic iron levels. Thereafter, hepcidin frequently affects duodenal cells for dietary iron t [....] » Read More
Extranodal marginal zone lymphomas (EMZL) originate in the post germinal centers of the B-cell marginal zone and have a tendency to develop in various epithelial tissues. Gastric marginal zone lymphoma (GMZL) is the most common subtype, accounting for 75% of Gastrointestinal lymp [....] » Read More
In this work, a comparative analysis of the matrix metalloproteinase (MMP) gene polymorphisms associations with peptic ulcer disease (PUD) in men and women was carried out. Material and methods. The study sample included 305 men (188 PUD patients, 117 control) and 441 women (211 [....] » Read More
Pseudomyxoma peritonei (PMP) is a rare malignant disease, involving the peritoneum, characterized by the production of large quantities of mucinous ascites. PMP has a low incidence of 2-4 per million people, it’s challenging to diagnose, and has a limited prognosis. Normall [....] » Read More
Hirschsprung’s Disease and Anorectal malformations each represent 1 in 5,000 births in the pediatric population. These conditions require surgical intervention in the neonatal period with postoperative challenges including fecal incontinence, constipation, and affected qual [....] » Read More
In this work, the features of associations of candidate genes polymorphic variants with the formation of peptic ulcer disease (PUD) in men and women living in the Central Chernozem region of Russia are analyzed. The sample consisted of 305 men (188 – patients, 117 [....] » Read More
Chilaiditi Syndrome is a rare disease with an incidence of 0.025-0.28% cases, where it shows colon interposition between diaphragm and liver. Usually related to weakness, or elongation of suspensory ligaments of transversal colon, or the absence in congenital malformation. The 83 [....] » Read More
Intracellular double-stranded RNA (dsRNA) is recognized by mammalian cells to be viral in origin and leads to an immune response through intracellular pattern recognition receptors (PRRs). Human nuclei produce endogenous double stranded RNA from simian retroviruses that represent [....] » Read More
Japanese traditional martial arts (kobujutsu) have long been handed down through history and tradition. For example, an elderly person in his 80s can easily lift a person twice his own weight using Japanese kobujutsu. However, the methods have not been scientifically proven, and [....] » Read More
Background: Esophagogastroduodenoscopy (EGD) is the diagnostic imaging procedure of choice in the work-up of gastric carcinoma and chronic atrophic gastritis. Specialized personnel are scarce in areas of high occurrence and late diagnosis is frequent. Serum pepsinogen concentrati [....] » Read More
There are around 19 million US Veterans alive today, which is about 7 percent of the US adult population. Veterans ranging from 18 to over 100 years of age have served and deployed around the world over the last century in support of a variety of combat and non-combat operations [....] » Read More
Gastric ulcer is considered one of the high-risk diseases linked with the current lifestyle, while supplementation of natural antioxidants could affect the progression of gastric ulcer. In the current work, a novel aqueous extraction of beetroot, as a source of natural antioxidan [....] » Read More
Background/aims: The association of chronic inflammatory bowel disease (IBD) and celiac disease (CD) has been exceptionally described in the literature. These are two chronic digestive diseases with complex etiopathogeny; their association in the same patient is rare, posing a [....] » Read More
Acute Pancreatitis (AP) is a medical condition that requires prompt diagnosis and treatment. Its diagnosis requires at least two of the following three criteria: Acute abdominal pain, serum lipase/amylase ≥ 3 times of normal, and imaging consistent with pancreatitis. High morb [....] » Read More
Background: Antibiotics alone are often insufficient to treat C. difficile infection (CDI) because they have no effect on C. difficile spores that germinate within a disrupted microbiome. SER-109, an investigational, oral microbiome therapeutic comprised of purified Firmicutes sp [....] » Read More
Introduction: Klatskin's tumor is a cholangiocarcinoma that develops from the right or left bile ducts and the upper part of the main bile duct. They are usually diagnosed at an advanced, inoperable stage, and have an extremely poor prognosis. Biliary drainage is proposed in [....] » Read More
Introduction: Echo-endoscopy is an essential technic in the exploration of anomalies of the bilio-pancreatic tract. However, it causes problems of availability and expertise of operators. The aim of our study is to specify the place of echo-endoscopy in the etiological diagnosis [....] » Read More
Background Gallstones acute pancreatitis has increased incidence in young women in the 2 years postpartum. Middle aged women with longer period of breastfeeding have less hospitalization for gallbladder disease. Methods We identified all sicilian women who delivered (201 [....] » Read More
Hepatocellular adenoma (HCA) is a rare benign liver neoplasm associated with the use of oral contraceptives, which could be complicated by bleeding and malignant transformation. Common clinical manifestations of HCA includes abdominal pain, a incidental palpable liver mass, or sh [....] » Read More
Introduction: Both HIV and HCV (Hepatitis C virus) may induce metabolic disorders and cause liver complications. Therefore, we aim to analyze the metabolite differences among treatment naïve HIV/HCV co-infected patients with versus without liver disease progression (LDP) and [....] » Read More
As a vital component of gastroenterology and endoscopology, minimally invasive endoscopic surgery has expanded its technology from surface to depth, from inside to outside, from intraluminal to extraluminal lesions, and from organic diseases to functional diseases. We summarize t [....] » Read More
Artesunate (Art), an antimalarial drug, has demonstrated its protective effects against ischemia/reperfusion (I/R) injury in various organs, but its potential function against hepatic I/R is still unknown. This study, hence, examined whether treatment with Art alone or in combina [....] » Read More
The relationship between liver and other organs, liver-related diseases and the time factors for pathogenesis of liver disease were analyzed and extracted from the research data of Chinese Traditional Medicine and modern medical science. The other organs related [....] » Read More
The accumulation of extracellular matrix (ECM) proteins in the liver lead to liver fibrosis and endstage liver cirrhosis. C-C motif chemokine receptor 2 (CCR2) is an attractive target for treating steatohepatitis. However, limited investigations have been conducted to explore the [....] » Read More
The small intestinal digestion has been a subject matter of interest to many researchers since its discovery. One of the first discoveries of bowel motion was reported by WB Cannon in his publication, “The movements of the intestines studied by means of the Rontgen ra [....] » Read More
Background: The prevalence of liver complications is increasing among people living with HIV (PLWH) where microbial translocation (MT) might play a vital role. We conducted a prospective cohort study aiming to evaluate association between plasma biomarkers of MT and liver fibrosi [....] » Read More
Transforming growth factor-beta1 (TGF-β 1) is a critical homeostasis regulator aberrantly activated during inflammation, fibrosis, and carcinogenesis. Causative agents of chronic liver diseases, such as viral infection, alcohol, and co-morbidities, such as diabetes and obesi [....] » Read More
Hepatic encephalopathy (HE) is a neuropsychiatric syndrome resulting from impaired liver function. There is wide range of neuropsychiatric disturbances following HE, ranging from minimal alteration in the personality to the complex changes in the brain function leading to impairm [....] » Read More
Pancreatic cancer is one of the most important neoplasm in Western countries and it is the fourth cause of death from cancer. The radical surgical resection is the only curative option, but unfortunately more than 80% of patients presents unresectable disease to hospital access. [....] » Read More
Gastric cancer is the second commonest cause of death among all cancers and the fifth most common cancer in the world. The number of deaths due to gastric cancer is about 723,000 annually. It is more common in men compared to women. The incidence of gastric cancer has 20-fold var [....] » Read More
Fungi present in the human gut play a dual role in health. They make up the gut mycobiome. Their presence as commensals in gut is influenced by type of diet and other factors like excess use of orally acting antibacterial agents. Some yeast strains like Saccharomyces boulardii ca [....] » Read More
Gastro-Esophageal Reflux Disease (GERD) is one of the most common gastrointestinal complaints. The disease leads to troublesome symptoms such as heartburn and regurgitation and has a chronic, relapsing disease course. Among various natural compounds that have been used in this [....] » Read More
Helicobacter pylori (H. pylori) colonizes the mucus layer of the human stomach in nearly half of the world's population. In Sudan, a variety of sociodemographic factors contribute to a steady increase in the prevalence rate of H. pylori infection, which ranges from 48% to 65. [....] » Read More
Acute cholecystitis, though a common surgical presentation, may have a rare etiology such as IgG4-Related-Disease [1]. Usually IgG4-Related-cholecystitis is associated with involvement of pancreas or biliary tree. Recently, we came across two cases of isolated IgG4-Related-Ac [....] » Read More
CRC are among the common cancers all over the world both in incidence and as a cause of death. A form of genomic instability, occurs through the insertion or deletion of repeating nucleotides during DNA replication and failure of the mismatch repair system to corre [....] » Read More
The expression of c-Myc, at both gene and protein levels, has been reported in hepatocellular carcinoma (HCC) and different tissue tumors. This protein functions in the control of cellular mass, differentiation, and apoptosis. To better understand the relationship between mitogen [....] » Read More
Introduction: Amyloidosis is an extremely rare disease frequently diagnosed at an advanced stage, resulting in significant morbidity and mortality. Gastrointestinal amyloidosis can present with unintentional weight loss, diarrhea, abdominal pain, malabsorption, gastroesophageal r [....] » Read More
Title : Co-inhibitory immune checkpoints in celiac disease
Maria Isabel Torres Lopez, University of Jaen, Spain
Immune checkpoints are regulators of key processes in the immune system. These molecules represent the modulators of the signalling pathway responsible for immunological tolerance, a concept that prevents the destruction of "auto" cells by the immune system. Specificall [....] » Read More
Title : The chyliferous vessels; From “De lactibus sive de lacteis venis” to the clinics of today
Lorenzo Ricolfi, Medical Clinic in Bordighera, Italy
In 1622, while vivisecting a dog previously subjected to a poor diet, the famous Italian anatomist, Gaspare Aselli, accidentally noticed the presence of numerous vessels with milky contents in the intestine. He reported his experimental research in "De lactibus sive de lacte [....] » Read More
Title : Formulation of odoribacter splanchnicus for oral colon delivery: Manufacturing and in vitro evaluation
Saliha Moutaharrik, Università degli Studi di Milano, Italy
Gut microbiome is gaining increasing interest as an innovative field of research mainly because of the growing evidence on implications of its alteration in a variety of diseases, ranging from intestinal to cardiovascular and brain ones. Therefore, identification and replenishmen [....] » Read More
Title : Molecular pathogenesis of IBD associated colon cancer
Ru Chen, Baylor College of Medicine, United States
The inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, and are associated with an elevated rate of developing colitis-associated colorectal cancer (CAC). Although the precise etiology and pathogenesis of CAC are not completely under [....] » Read More
Title : The role of transforming growth factor-?1 signaling pathway during the process of angiogenesis induced by chronic stress in colorectal cancer
Zhang Jie, Chongqing Medical University, China
Chronic stress could induce stress-related hormone (SRH), including norepinephrine (NE). In this study, chronic restraint stress (CRS) was demonstrated to attenuate the efficacy of bevacizumab and promote tumor growth and angiogenesis in a colorectal tumor model. Propranolol, blo [....] » Read More
Title : Investigating healthcare inequalities in pancreatic cancer: Insights from the global burden of disease study in low-sdi nations
Pojsakorn Danpanichkul, Chiang Mai University, Thailand
Pancreatic cancer represents a significant global health challenge, particularly in regions with low sociodemographic indices (SDI). This investigation leverages data from the Global Burden of Disease (GBD) study to analyze the prevalence, mortality, and disability-adjusted life [....] » Read More
Title : Clinicopathological characteristics and prognosis analysis of ovarian metastases in colorectal cancer: A single center experience
Zhu Jing, Chongqing Medical University, China
Purpose This study aimed to improve the management of ovarian metastases (OM) in colorectal cancer (CRC) by evaluating the clinicopathological characteristics, therapeutic strategies, and prognostic factors associated with OM originating from CRC. Methods Medical records of pa [....] » Read More
Title : Study on the expression and relationship of CD24, CD47, and PD-L1 in HBV-associated hepatocellular carcinoma
Xueping Huang, Fujian Provincial Hospital, China
Background and purpose: Hepatocellular carcinoma (HCC) is one of the most common and invasive malignancies, and hepatitis B virus (HBV) infection is the leading risk factor of HCC worldwide. Currently, immune checkpoint inhibitor (ICI) therapy is the new standard treatment for a [....] » Read More
Title : Disparities in access to healthcare and outcomes for early onset colorectal cancer patients in low-income countries.
Pojsakorn Danpanichkul, Chiang Mai University, Thailand
Early onset colorectal cancer (EOCRC) among individuals under 50 years of age has emerged as a major global health concern, with a rising incidence in low sociodemographic index (SDI) countries. This study examines the Global Burden of Disease (GBD) data from 2000 to 2019 to prov [....] » Read More
Title : A serine peptidase from burkholderia gladioli with hydrolytic activity toward celiac disease- eliciting pro-immunogenic peptides and potency enhancement through modification of its active site pocket
Yu You Liu, National Chung Hsing University, Taiwan
Celiac disease is an autoimmune disease triggered by oral ingestion of gluten found inside wheat, barley, and rye grains. Gluten is a water-insoluble protein group composed of ethanol-soluble prolamins and ethanol-insoluble glutelins. The most common prolamins are the ones in whe [....] » Read More
Title : Antibiotic resistance profile of helicobacter pylori to 14 antibiotics: A multicenter study in Fujian, China
Xueping Huang, Fujian Provincial Hospital, China
Aim: Efficacy of Helicobacter pylori (H. Pylori) eradication is related to the local antimicrobial resistance epidemiology. Our aim was to investigate the antibiotic resistance of H. Pylori in Fujian, China. Methods: H. Pylori -infected patients in four centers in F [....] » Read More
Title : Microbiome and neurotrauma: Emerging innovations
Brandon Lucke Wold, University of Florida, United States
The gut-brain axis plays an important role in bidirectional communication that exists and can be altered by injury. Neurotrauma provides acute alteration in the GI tract and alters autonomic function. In this focused review, we highlight what is known about GI disruption followin [....] » Read More
Title : Incidence trend of colorectal cancer among screening age group in the United States: An observational study from seer database 2009-2019
Bibek Karki, Hurley Medical Center/MSU, United States
Background Colorectal cancer (CRC) is a major public health concern in the United States. We conducted an observational study to examine the incidence trend of CRC over the past decade, with a focus on age, sex, race, and median household income. Methods We used the Surveillan [....] » Read More
Title : Characterizing the molecular and physiological changes associated with colorectal cancer in wistar rats
Ana Faustino, University of Evora, Portugal
The high mortality rate associated with colorectal cancer (CRC) underscores the need for improved diagnostic and therapeutic approaches. To this end, animal models are invaluable tools for enhancing our understanding of the disease, as they can be used to gain insights into disea [....] » Read More
Title : Hartmann’s procedure: Hard to revise?
Akshay Bavikatte Prasannakumar, SLP Fellow Harvard Medical School, India
AIM: The Hartmann's procedure is commonly regarded as a two-stage procedure. This study aims to evaluate the outcome of the Hartmann's procedure with respect to the rate of reversal and associated morbidity. METHODS: This retrospective study analyzed all patients who und [....] » Read More
Title : Redefining gastrointestinal pathogenicity with crohn’s diseases
Gilles R G Monif, University of Florida, United States
Crohn’s disease is an experiment in nature that has identified a new mechanism by which an exogenous organism, Mycobacterium Avium subspecies Paratuberculosis (MAP), can produce disease within the gastrointestinal tract. Once it was evident that disruption of the immune sys [....] » Read More
Title : Which to choose pre incisional or post incisional bupivacaine for pain relief in patients undergoing elective surgery
Muhammad Bilal Akbar, Dr.Grays Hospital NHS Grampian, United Kingdom
Background: Pain is the most important concern after surgical intervention that needs to be addressed for better compliance and early mobilization to avoid complications. The need of better analgesic and timings of its administration is the key to success. Objective: To [....] » Read More