Title : Does gender matter in colorectal cancer?
Abstract:
Colorectal cancer is one of the most common and lethal cancer worldwide, and it exhibits differences in incidence, pathogenesis, molecular pathways, and outcome depending on the location of the tumour. Colorectal cancer is a disease strongly influenced by gender, mortality rates in males considerably higher than females
Aim: To determine the gender disparities in the incidence of Colorectal cancer
Methods: All patients managed with colorectal cancer from January 2015 through December 2019 were retrospectively identified from the referral database created by the colorectal specialist nurses in the colorectal service.
Inclusion: All patients diagnosed with colorectal cancer
Exclusion: Tumour in the Appendix, Anal canal, small bowel, metastatic tumours of unknown primary
Results:
976 patients were diagnosed with bowel cancer percentages of studied participant were Male 52.60% and Female 47.40%. The mean age of 74.14 years. Sixty six (66) 6.76% patients were excluded from the study. The location of colon cancer is also changing. The incidence rate of Right side colon cancer in women was much higher than that in men 1.20:1, and on Left side colon cancer including rectum was much higher in men than that in women this was especially exhibited in cases of rectal cancer, for which the male to female ratio was increased to 1.54:1 whereas the male to female ratio of left colon cancer 1.26:1 The incidence rates were increasing in all groups over time, especially in the 50 -79 years group. Incidence of colorectal cancer was greater for cancers of the left side of colon than right colon (62.41% vs 37.58%).
Conclusion:
There are not significant sex differences in access to and effectiveness of Colorectal cancer treatment. Screening provides effective opportunity to prevent Colorectal cancer. Gender-specific guidelines for screening, treatment, and prevention protocols for colorectal cancer can be established to decrease the mortality and increase the quality of life.
