HYBRID EVENT: You can participate in person at Baltimore, MD, USA or Virtually from your home or work.

2nd Edition of International Conference on Gastroenterology

October 21-23, 2024, Baltimore, Maryland, USA

October 21 -23, 2024 | Baltimore, MD, USA
Gastro 2023

Immune Check point Inhibitor(ICI) in Colorectal Ca(CRC)

Speaker at Gastroenterology Conference - Kakil Rasul
National Center for Cancer Care and Research, Qatar
Title : Immune Check point Inhibitor(ICI) in Colorectal Ca(CRC)

Abstract:

CRC are among the common cancers all over the world both in incidence and as a cause of death. A form of genomic instability, occurs through the insertion or deletion of repeating nucleotides during DNA replication and failure of the mismatch repair system to correct errors in nucleotide repeat markers, patients with functional MMR mechanisms are MSS or pMMR.  About 8-10 % of all CRCs have dMMR activity this is due to inactivating “events” to one of several DNA MMR genes MSH2 and MLH1 (the“major” DNA MMR genes ) MSH6 and PMS2 (the “minor” DNA MMR genes) dMMR) Will present a cohort of patient with dMMR with highlight on response rate and survival supported by  clincal response and images and lab test.

 Audience Take Away: 

  • This data provides the framework for immuno- therapy in CRC
  • Highlights the clinical impact of biomarker driven therapy in CRC
  • The tumor agnostic mismatch repair deficiency population of CRC has the potential eliminate the need for chemotherapy, radiation and surgery

Biography:

Kakil Rasul was worked Senior consultant in Haem/ Oncology NCCCR , Hamad Medical Corporation Doha, Qatar and Associate prof. in clinical medicine at Weil Cornell Medical College in Qatar; Leading the Hepatobiliary pancreatic Multidisciplinary team Hamad Medical Corporation; Core Member of the Gastrointestinal Multidisciplinary team , Hamad Medical.

Corporation: Active member of ESMO , ASCO; Core member of both colorectal hepatobiliary MENA-NCCN guidelines panels for development of the guideline modifications; Member of the editorial board for the World Journal of Oncology Research and Advance in modern oncology research journal, journal of hepatology research; Reviewer for many journal : ASCO educational book , British Journal of Medicine Research , Saudi Medical Journal, Annals of Saudi Medicine , and Qatar Medical Journal. Invited as speaker in many conferences international and regional and Publications Published more than 80 articles in peer reviewed international and regional journals.

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