GASTRO 2024_ Event Postponement

This is to inform that due to some circumstances beyond the organizer control, “2nd Edition of International Conference on Gastroenterology” (Gastro 2024) during October 21-23, 2024 at Baltimore, MD, USA has been postponed. The updated dates and venue will be displayed shortly.

Your registration can be transferred to the next edition, if you have already confirmed your participation at the event.

For further details, please contact us at gastroenterology@magnusconference.com or call + 1 (702) 988-2320.

HYBRID EVENT: You can participate in person at Baltimore, MD, USA or Virtually from your home or work.

2nd Edition of International Conference on Gastroenterology

October 21-23, 2024, Baltimore, Maryland, USA

October 21 -23, 2024 | Baltimore, MD, USA
Gastro 2023

Human enteroids/colonoids and intestinal organoids functionally recapitulate normal intestinal physiology and pathophysiology

Speaker at GI Conferences - Rodrigo Cristofoletti
Rodrigo Cristofoletti
University of Florida, United States
Title : Human enteroids/colonoids and intestinal organoids functionally recapitulate normal intestinal physiology and pathophysiology

Abstract:

Identification of Lgr5 as the intestinal stem cell marker as well as the growth factors necessary to replicate adult intestinal stem cell division has led to the establishment of the methods to generate "indefinite" ex vivo primary intestinal epithelial cultures, termed "mini-intestines." Primary cultures developed from isolated intestinal crypts or stem cells (termed enteroids/colonoids) and from inducible pluripotent stem cells (termed intestinal organoids) are being applied to study human intestinal physiology and pathophysiology with great expectations for translational applications, including regenerative medicine. Here we discuss the physiologic properties of these cultures, and potential applications.

Biography:

Rodrigo Cristofoletti, Ph.D., joined the University of Florida in 2020 as assistant professor in the Center for Pharmacometrics and Systems Pharmacology (Orlando) in the Department of Pharmaceutics. He received his B.S. in Pharmaceutical Sciences from the University of Sao Paulo, Brazil in 2004. Dr. Cristofoletti received his Ph.D. summa cum laude from the Johann Wolfgang Goethe University (Frankfurt am Main, Germany). The Clinical Pharmacology & Biopharmaceutics Office of the Brazilian Drug Regulatory Agency (ANVISA) has been Dr. Cristofoletti’s place of employment for the last 15 years. Currently, Dr. Cristofoletti’s lab focus on translational DMPK research and disease modeling.

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