HYBRID EVENT: You can participate in person at Orlando, FL, USA or Virtually from your home or work.

International Conference on Gastroenterology

April 20-22, 2023

April 20 -22, 2023 | Orlando, Florida, USA
Gastro 2023

Hamdy M. Aly

Speaker at Gastroenterology 2023 - Hamdy M. Aly
Pharmacology & Toxicology Department, Egypt
Title : Modulation of ischemic preconditioning on hepatocytes following hepatic ischemia- reperfusion injury in adult albino rat and the possible role of electrolytes composition in attenuating the ischemia


Ischemia reperfusion (I/R) injury is a pathophysiologic process whereby hypoxic organ

damage is accentuated following return of blood flow and oxygen delivery to the compromised tissue.

Transient episodes of hepatic ischemia occur during solid organ transplantation, trauma, hypovolemic

shock, and elective liver resection, when inflow occlusion or total vascular exclusion is used to minimize

blood loss.

The ischemia causes injury to the hepatocytes which includes both direct cellular damage as the result

of the ischemic insult as well as delayed dysfunction and damage resulting from activation of

inflammatory pathways. Upon reperfusion