Cholestasis

Cholestasis is a medical condition in which the flow of bile from the liver to the small intestine is blocked or reduced. Bile is an important fluid that helps to digest and absorb fats and certain vitamins. When it is blocked, it can cause a buildup of bile acids in the body, which can result in a variety of symptoms such as jaundice, dark urine, itching, nausea, and abdominal pain. Cholestasis can be caused by a variety of conditions, including liver disease, certain medications, and certain birth defects. The most common form of cholestasis is intrahepatic cholestasis, which is caused by a blockage in the bile ducts inside the liver. This blockage prevents the bile from reaching the small intestine. Extrahepatic cholestasis is caused by a blockage outside of the liver, such as in the gallbladder or bile ducts. Treatment for cholestasis depends on the underlying cause. For example, if it is caused by a medication, the doctor may recommend discontinuing the medication or switching to a different one. If it is caused by a liver disease, the doctor may recommend dietary changes or medications to help manage the condition. In some cases, surgery may be necessary to remove a blockage or to repair or replace a damaged liver. Cholestasis can be a serious condition, so it is important to seek medical attention as soon as possible if you think you may be experiencing cholestasis. With proper diagnosis and treatment, most people with cholestasis can recover and experience improved symptoms.