Inflammation of the gastrointestinal tract is a complex biological response to harm caused by bacteria, damaged cells, or irritants. The symbiotic microbiome in the digestive tract is thought to protect the gut by eliminating unwanted stimuli and promoting recovery. The presence or lack of a microbiome can cause type 2 immunity to be worsened, as well as allergic/infectious and inflammatory consequences, including parasitic diseases. Inflammation of the gastrointestinal tract is frequently accompanied by changes in vascular anatomy and function. Microvascular congestion, Dilatation of the arteries supplying the tissue, and excessive fluid and protein leakage with interstitial oedema are examples of these disorders. IBD medications can often reduce inflammation and improve intestinal healing, leading in remission—long-term symptom relief. Many persons with IBD, however, have a chronic illness that requires lifelong therapy.