Chronic liver failure is a long-term condition that involves the gradual loss of liver function due to a variety of underlying causes. It is a progressive disorder that can lead to cirrhosis and end-stage liver failure. Common causes of chronic liver failure include viral hepatitis, alcohol abuse, fatty liver disease, and autoimmune liver disease. Symptoms of chronic liver failure can include fatigue, jaundice, abdominal pain, loss of appetite, and ascites. The diagnosis of chronic liver failure is made based on medical history, physical examination, laboratory tests, and imaging studies. Common laboratory tests used to diagnose chronic liver failure include liver function tests, liver biopsy, and imaging studies such as ultrasound and CT scan. Treatment of chronic liver failure is dependent on the underlying cause and can include lifestyle modifications, medications, and surgery. Lifestyle changes such as abstaining from alcohol, eating a healthy diet, and exercising regularly can help improve liver function and slow the progression of chronic liver failure. Medications such as antiviral drugs, steroids, and immune system suppressants may be used to treat the underlying cause of the condition. In cases of advanced liver failure, a liver transplant may be necessary. Chronic liver failure can be a serious and life-threatening condition if left untreated. It is important for individuals at risk for chronic liver failure to seek medical attention and follow their doctor's advice. Early diagnosis and treatment can help reduce the risk of complications and improve patient outcomes.