Biliary and gallbladder diseases are common causes of abdominal pain, jaundice, and infection. Conditions such as gallstone disease, cholecystitis, cholangitis, and biliary strictures require timely diagnosis and intervention to prevent complications. Advances in imaging and endoscopic techniques have improved diagnostic precision and therapeutic outcomes. Management approaches range from conservative treatment to minimally invasive surgical and endoscopic procedures. This topic explores current best practices, emerging technologies, and multidisciplinary approaches to managing biliary and gallbladder disorders.