Precision gastroenterology represents a paradigm shift from generalized treatment strategies toward individualized, data-driven care. By integrating clinical phenotypes, genetic information, molecular biomarkers, microbiome profiles, and environmental factors, clinicians can better predict disease behavior and therapeutic response. Advances in multi-omics technologies, artificial intelligence, and digital health tools are enabling earlier diagnosis, personalized treatment selection, and improved disease monitoring. Precision approaches are increasingly applied in inflammatory bowel disease, gastrointestinal cancers, liver disease, and functional GI disorders. Biomarker-guided therapy, treat-to-target strategies, and risk-based surveillance are becoming central to modern practice. This topic explores the role of emerging technologies in enabling precision medicine, the challenges of data integration and implementation, and the future direction of personalized gastrointestinal care.
Title : Gastroenterology viewed through a glass darkly: An IDI perspective
Gilles R G Monif, University of Florida, United States
Title : The psychology of disorders of gut-brain interactions
Tracy E Hill, Ph.D. & Associates LLC, United States
Title : How epigastric impedance would radically change gastric medicine
John Andrew Sutton, Gastria Ltd, United Kingdom
Title : Role of Pregnancy (P) and breastfeeding on Gallstones (GS) related Acute Pancreatitis (AP)
Alberto Maringhini, La Maddalena, Italy
Title : From the birth of atoms to life: Iodine and caesium, angels and demons of evolutionary biology, in pancreatic cancer and diabetes
Venturi Sebastiano, AUSL-ROMAGNA, Italy
Title : The IL17REL gene encodes a decoy receptor of IL-17 family cytokines to control gut inflammation
Youcun Qian, Shanghai Institute of Nutrition and Health, China