Primary liver cancer and advanced hepatobiliary malignancies represent a growing global health challenge, driven by chronic liver disease, viral hepatitis, and metabolic disorders. Early detection remains difficult, and many patients present with advanced disease. Advances in imaging, molecular profiling, and staging systems have improved diagnostic accuracy and treatment planning. Therapeutic options now include locoregional therapies, systemic targeted agents, immunotherapy, and combination approaches. Multidisciplinary care involving hepatology, oncology, surgery, and interventional radiology is essential for optimal management. Ongoing research focuses on identifying predictive biomarkers, overcoming treatment resistance, and improving survival in advanced disease. This topic explores evolving strategies in hepatobiliary oncology, emphasizing precision medicine and integrated care models.
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Youcun Qian, University of Chinese Academy of Sciences, China
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Jose Luis Braga De Aquino, Pontifical Catholic University of Campinas, Brazil
Title : The efficacy of fermented foods as an adjunct therapy in ulcerative colitis - a literature review
Jack D Doorly, Alfred Health, Australia
Title : Professional dining and health
Yaffa Machnes, Bar-Ilan University, Israel
Title : How epigastric impedance would radically change gastric medicine
John Andrew Sutton, Invention City, United States
Title : Differentiating simple and aggressive phenotypes of metabolic dysfunction-associated steatotic liver disease utilizing bioelectrical impedance-derived metabolic age gap
Yury Marakhouski, Belarusian State Medical University, Belarus