Eosinophilic esophagitis (EoE) is an inflammatory disorder of the esophagus. It is characterized by an increased number of eosinophils, a type of white blood cell, in the esophageal tissue. Symptoms of EoE include difficulty swallowing, food getting stuck in the throat or chest, vomiting, and abdominal pain. EoE can also cause damage to the esophagus. EoE is thought to be an allergic reaction to food or environmental allergens. The most common allergens associated with EoE are dairy, wheat, soy, eggs, and nuts. Other potential triggers include environmental allergens, such as dust mites, molds, and pet dander. Diagnosis of EoE is made through a combination of medical history, physical exam, endoscopy, and biopsy. Endoscopy is a procedure used to look at the esophagus and take small tissue samples for testing. During the biopsy, tissue samples are examined under a microscope. Treatment of EoE is focused on reducing inflammation and controlling symptoms. Treatment may include dietary modifications, medications, and/or allergy shots.
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