Helicobacter pylori (H. pylori) is a bacterium that lives in the stomach and duodenum. It is one of the most common causes of peptic ulcers and is also linked to stomach cancer, non-ulcer dyspepsia, and inflammation of the stomach lining. H. pylori is a spiral-shaped, Gram-negative bacterium that is most commonly acquired through contaminated food or water. H. pylori infection is usually asymptomatic, however, in some cases, it can cause abdominal pain, nausea, vomiting, and occasional bleeding. Other symptoms of H. pylori infection may include bloating, belching, acid reflux, and a burning sensation in the stomach. It is important to note that the majority of people infected with H. pylori never develop any of these symptoms. The diagnosis of H. pylori infection is often made through a blood, stool, or breath test. Treatment typically involves antibiotics, as well as medications to reduce stomach acid production. In some cases, surgery may be necessary.