Hepatitis E is an infectious disease caused by the hepatitis E virus (HEV). It is mainly spread through contaminated water and is most common in countries with poor sanitation. It is a liver disease that can cause mild to severe symptoms, including fever, fatigue, nausea, abdominal pain, and jaundice. In some cases, it can lead to liver failure and death. HEV is a single-stranded RNA virus that belongs to the genus Orthohepevirus. It is primarily spread through the fecal-oral route, either directly through contact with an infected person or indirectly through contaminated food or water. The virus can also be transmitted from mother to child during pregnancy or through blood transfusions. Unlike other forms of hepatitis, there is no vaccine available to prevent hepatitis E. The best way to protect yourself is to practice proper hygiene, including frequent hand washing and avoiding contact with contaminated water. It is also important to ensure that food is cooked properly and that water is safe to drink. In most cases, the symptoms of hepatitis E will resolve on their own within 4-6 weeks. However, in some cases, the virus may cause chronic liver disease or liver failure. In rare cases, it can even lead to death. Treatment typically involves supportive care, such as rest, fluids, and medications to reduce liver inflammation. In conclusion, hepatitis E is a serious liver infection caused by the hepatitis E virus. It is most commonly spread through contaminated water and is most common in countries with poor sanitation. While there is no vaccine available to prevent it, practicing proper hygiene and avoiding contact with contaminated water can help reduce the risk of infection.