Hepatocytes are specialized cells that make up the majority of the liver, which functions as the body's main organ for metabolism and detoxification. They are responsible for a variety of functions, including the production of bile, the storage and processing of fats, proteins, and carbohydrates, and the synthesis of hormones and other proteins. Hepatocytes are highly dynamic cells, capable of rapid and large scale changes in their metabolic activities, which are largely regulated by hormones, growth factors, and other extracellular signals. They contain several types of organelles, including mitochondria, lysosomes, and endoplasmic reticulum. The mitochondria are responsible for energy production in the form of ATP, while the lysosomes contain digestive enzymes that break down proteins and lipids. The endoplasmic reticulum is responsible for protein synthesis and the transport of proteins and lipids to the Golgi apparatus. Hepatocytes also contain special structures called canaliculi, which are small channels that connect adjacent cells, allowing for the exchange of metabolites and secreted proteins. They also contain numerous enzymes, which are responsible for a wide range of metabolic processes including the synthesis of cholesterol and triglycerides.
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Title : Nanoemulsions as a strategy to enhance gastrointestinal bioavailability and bioactivity of lipid based nutraceuticals
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Title : Sickle cell liver disease: A multidisciplinary hemato-hepatology approach
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Title : From the birth of atoms to life: Iodine and caesium, angels and demons of evolutionary biology, in pancreatic cancer and diabetes
Venturi Sebastiano, Department of Public Health of Romagna, Italy