HYBRID EVENT: You can participate in person at London, UK from your home or work.

2nd Edition of International Conference on Gastroenterology

September 24-26, 2026, London,UK

September 24 -26, 2026 | London, UK

Lower Esophageal Sphincter

Lower Esophageal Sphincter

The lower esophageal sphincter (LES) is a muscular valve that acts as a gatekeeper between the esophagus and the stomach. It is located at the bottom of the esophagus, just above the stomach. The LES is essential to normal digestion and is responsible for preventing stomach contents, including acid and bile, from refluxing up the esophagus. The LES is composed of two layers of muscle fibers and is controlled by both the autonomic nervous system and hormones. When food enters the stomach, the LES relaxes and allows the food to pass through. It then quickly contracts to prevent the stomach contents from traveling back up the esophagus. The LES normally remains tightly closed except for when food passes through it. If the LES does not close properly or relaxes too often, it can lead to gastroesophageal reflux disease (GERD). GERD is a condition that causes the contents of the stomach to travel back up the esophagus and can cause symptoms such as heartburn, regurgitation, and chest pain. The LES can be affected by various factors such as diet, smoking, alcohol consumption, and certain medications. In some cases, GERD can be treated by lifestyle modifications, such as avoiding acidic foods, eating smaller meals, and avoiding lying down after eating. In more severe cases, medications and surgery may be needed to repair the LES and prevent GERD. The lower esophageal sphincter is an important part of the digestive system and is essential for normal digestion. If it does not function properly, it can lead to a variety of digestive issues. It is important to consult a doctor if you experience any of the symptoms associated with GERD so that the underlying cause can be addressed.

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