Pancreatic diseases are disorders that affect the pancreas, a large organ located behind the stomach that produces digestive enzymes and hormones that regulate blood sugar. Pancreatic diseases can include pancreatic cancer, pancreatitis, cystic fibrosis, and diabetes. Pancreatic cancer is the most common and is the fourth leading cause of cancer death in the United States. Pancreatitis is an inflammation of the pancreas, which can be caused by gallstones, alcohol use, or certain medications. Cystic fibrosis is an inherited disorder that causes a buildup of thick, sticky mucus in the pancreas, leading to damage to the organ. Diabetes is a condition in which the pancreas does not produce enough insulin, the hormone that helps regulate blood sugar. Treatment for pancreatic diseases varies depending on the diagnosis and severity. Pancreatic cancer is often treated with surgery, chemotherapy, and radiation, while pancreatitis is treated with medications and lifestyle changes. Cystic fibrosis is treated with medications, physical therapy, and a specialized diet. Diabetes is typically managed with medications, regular blood sugar monitoring, and lifestyle changes such as healthy eating and regular physical activity. It is important to talk to your doctor if you have symptoms or risk factors for pancreatic diseases, such as a family history of pancreatic cancer or diabetes, or heavy alcohol use. Early diagnosis and treatment can help improve outcomes and reduce the risk of complications.