Ulcerative colitis is a type of chronic inflammatory bowel disease (IBD) that causes inflammation and ulceration in the lining of the large intestine (colon) and rectum. It is a lifelong condition that can have serious effects on the quality of life of those affected. The exact cause of ulcerative colitis is unknown, but it is believed to be an autoimmune disorder in which the body's immune system mistakenly attacks the cells of the intestine. Genetics may also play a role in the development of the disease. Common symptoms of ulcerative colitis include abdominal pain and cramping, diarrhoea (with or without blood), fatigue, weight loss, fever, and anaemia. Other symptoms may include joint pain, eye problems, and skin rashes. These symptoms may come and go, but the disease is considered chronic and can last for years. Treatment for ulcerative colitis typically involves lifestyle changes, such as dietary adjustments and stress reduction, and medications. The goal of treatment is to reduce inflammation, control symptoms, and maintain remission. Surgery may be recommended in severe cases.
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Youcun Qian, Shanghai Institute of Nutrition and Health, China